The song starts with an electric sitar playing the main riff of the song, before the drums and electric guitars come in. In addition to the use of a sitar, the loud "crack" heard at 0:30 in the song (and then repeatedly throughout the intro) is bassist Jason Newsted playing a 12-string electric bass, as mentioned by the bassist on the Classic Albums: Metallica - Metallica DVD.
The song is performed frequently during the band's live concerts, and was played with the San Francisco Symphony Orchestra (conducted by the late Michael Kamen) on the album S&M.
- In the PC game Warcraft III: Reign of Chaos, the Bandit unit quotes this song, saying "Roamer, wanderer, nomad, vagabond, call me what you will." and the Beastmaster hero says, "Where I lay my head is home. See that rock? That's my pillow."
- Koopsta Knicca, a former member of Three 6 Mafia, used some instrumental parts of this song for his song "Torture Chamber" from the album Da Devil's Playground.
- An instrumental cover version of this song can be found as track 5 on the 2005 album Hands Without Shadows by guitarist Michael Angelo Batio.
- Sinner covered the song for A Tribute to the Four Horsemen.
- Apocalyptica also covered this song on their album Plays Metallica by Four Cellos
- "Wherever I May Roam"
- "Fade to Black (Live)"
- "Wherever I May Roam (Demo)"
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